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Tiredeness and fatigue

£ 59.99

A comprehensive analysis of key healthcare markers including vitamin D levels, thyroid function and iron status which can all contribute to symptoms of tiredness and fatigue when dysregulated.

Tiredness & fatigue

Tests Included

Iron Status

Transferrin is produced by the liver and is a major protein that regulates the absorption and transportation of iron into and throughout the blood and body respectively. High levels of transferrin saturation are indicative of iron overload whilst low levels may coincide with iron deficiency.
A total iron-binding capacity (TIBC) test measures the blood's ability to attach itself to iron and transport it around the body. Individuals with iron deficiency will have low levels of iron but a raised TIBC. In comparison, those that have possess too much iron, for instance, in patients with iron overload syndrome, iron will be elevated but TIBC will be reduced or normal.
Measuring the amount of iron present in the blood is important in the diagnosis of conditions such as iron deficiency anaemia caused by a lack of iron to haemochromatosis which is caused by an overload of iron. Common symptoms of both elevated and reduced levels of iron include; muscle weakness, difficulty concentrating and fatigue. Other causes of reduced iron besides anaemia can be due to general blood loss. In contrast, a raised result can be indicative of an iron overload syndrome which may be the result of an inherited condition that results in the body storing too much iron, or the excessive consumption of iron supplements.
Ferritin is a protein that stores iron and releases it in a controlled fashion. In humans, it acts as a buffer against iron deficiency and iron overload. Plasma ferritin is also an indirect marker of the total amount of iron stored in the body, hence serum ferritin is used as a diagnostic test for iron-deficiency anaemia. Low levels are indicative of anaemia and may be caused by events such as excessive bleeding or lack of iron within the diet. In contrast, elevated ferritin levels could indicate iron overload syndrome or liver damage.

Inflamation marker

C-Reactive Protein (CRP) is a protein that increases in response to inflammation detected within the body - though it cannot be used to identify the exact location of where this inflammation is occurring. On the other hand, high Sensitivity CRP (CRP-hs) is used to detect low-level inflammation and can give more of an indication of the location of the inflammation as this type has been found to be associated with damaged blood vessels. Damage to blood vessels can increase an individuals likelihood of suffering a stroke or heart attack. Therefore, an elevated hs-CRP may be considered a risk factor for cardio-vascular disease.


Interestingly enough, vitamin D is in fact a hormone that is produced by the body and requires exposure to sunlight for activation. In addition. it can be found in certain foods such as egg yolks, fish and fortified dairy and grain products. Vitamin D is an essential component required for maintaining bone strength due to its role in aiding the intestines ability to absorb calcium. Low levels of vitamin D may be associated with secondary low bone mineral density and hyperparathyroidism. Consequently, these patients have a greater risk of suffering fractures and osteoporosis. Other conditions such as rickets and osteocalcin may also develop as a result of continued vitamin D deficiency over a long period of time.

Thyroid function


The purpose of this test is to measure the amounts of free thyroxine (T4) that is present within the blood. T4 is a one of two hormones that is secreted by the thyroid gland. Therefore, a high result may be associated with an individual with an overactive thyroid as more T4 is produced then normal. In contrast, a lower than normal result may arise if an individual has an underactive thyroid.


Thyroid Stimulating Hormone (TSH) is produced by the pituitary gland and acts to increase the functioning of the thyroid gland, This stimulation in turn encourages the production of triiodothyronine (T3) and thyroxine (T4) by the thyroid. Elevated TSH may be indicative of an underactive thyroid, In comparison, reduced TSH may be associated with an overactive thyroid.

How it works

Collect Sample

We send you an easy-to-use kit to collect your blood sample.

Post Sample

Post your sample to our lab in the prepaid envelope provided.

View Results

View results securely in your own personal dashboard.

About this test

Feeling tired at times is a completely normal process that occur for a variety of reasons such as; taking part in strenuous activity throughout the day, during events such as menstruation or the process of your body fighting an infection. However, in some cases, the feeling of lethargy can persist for a long period of time and can become chronic. Our tiredness and fatigue tracker tests for the most common conditions that are associated with feeling tired all the time, despite a good night’s rest. This includes testing for vitamin D deficiency, thyroid disorder and anaemia.

This test is perfect if:

  • You constantly feel tired, lacking energy throughout the day and would like to get down to the cause
  • You have noticed a sudden decrease in your energy levels and want to identify if it is being caused by a medical condition
  • You just want to make sure your levels of key hormones and analytes that are associated with fatigue and tiredness are within the healthy range

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